Evidence of behavioral, biological similarities between compulsive overeating and addiction

Drug Facts - Thu, 2019-10-17 10:52
Does yo-yo dieting drive compulsive eating? There may be a connection. According to researchers the chronic cyclic pattern of overeating followed by undereating, reduces the brain's ability to feel reward and may drive compulsive eating. This finding suggests that future research into treatment of compulsive eating behavior should focus on rebalancing the mesolimbic dopamine system -- the part of the brain responsible for feeling reward or pleasure.
Categories: Drug Facts

A rat's brain, on and off methamphetamine

Drug Facts - Wed, 2019-10-16 10:45
Drug addiction is a vicious cycle of reward and withdrawal. Chronic users often relapse because of the unpleasant physical and psychological symptoms they experience when they stop taking the drug. Now, researchers report metabolic changes in the brains of rats during methamphetamine self-administration and withdrawal that could help identify biomarkers and treatments for addiction.
Categories: Drug Facts

Potential therapy to treat detrimental effects of marijuana

Drug Facts - Tue, 2019-10-15 07:22
A new study using a preclinical animal model suggests that prenatal exposure to THC, the psychoactive component of cannabis, makes the brain's dopamine neurons (an integral component of the reward system) hyperactive and increases sensitivity to the behavioral effects of THC during pre-adolescence.
Categories: Drug Facts

New addiction treatments hold promise for stemming the opioid crisis

Drug Facts - Tue, 2019-10-08 09:59
Concerns over the opioid epidemic have sparked a strong scientific interest in why some people become addicted while others don't. Now, researchers are proposing novel treatment strategies that could help prevent abuse of opioids and other substances.
Categories: Drug Facts

Vaping-associated lung injury may be caused by toxic chemical fumes, study finds

Drug Facts - Wed, 2019-10-02 16:11
Research into the pathology of vaping-associated lung injury is in its early stages, but a study finds that lung injuries from vaping most likely are caused by direct toxicity or tissue damage from noxious chemical fumes.
Categories: Drug Facts

One third of patients with severe asthma are taking harmful doses of oral steroids

Drug Facts - Tue, 2019-10-01 16:22
A third of patients with severe asthma are taking harmful doses of oral steroids, according to a study of several thousand people in The Netherlands.
Categories: Drug Facts

Cannabis study reveals how CBD offsets the psychiatric side-effects of THC

Drug Facts - Mon, 2019-09-30 11:11
Researchers have shown for the first time the molecular mechanisms at work that cause cannabidiol, or CBD, to block the psychiatric side-effects caused by tetrahydrocannabinol (THC), the main psychoactive chemical in cannabis.
Categories: Drug Facts

Older adults with COPD more likely to use synthetic cannabinoids

Drug Facts - Mon, 2019-09-23 11:09
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that's often associated with a variety of health problems, including chronic muscle pain and insomnia. Psychoactive drug classes, like cannabinoids, are often prescribed to help reduce pain, promote sleep and decrease breathlessness. A study has found that older adults with COPD were twice as likely to use prescription synthetic oral cannabinoids compared to older adults without COPD, raising safety concerns.
Categories: Drug Facts

Alarming number of heart infections tied to opioid epidemic

Drug Facts - Wed, 2019-09-18 05:57
As the nationwide opioid epidemic continues, more young people are developing a life-threatening heart infection that can result from drug abuse. It predominantly affects young, white, poor men who also have higher rates of HIV, hepatitis C and alcohol abuse.
Categories: Drug Facts

A safer way for police to test drug evidence

Drug Facts - Tue, 2019-09-17 09:54
Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains illegal drugs without having to handle any suspicious contents directly. The new technique can limit the risk of accidental exposure to fentanyl and other highly potent drugs that can be dangerous if a small amount is accidentally inhaled.
Categories: Drug Facts

Brain cells that suppress drug cravings may be the secret to better addiction medicines

Drug Facts - Mon, 2019-09-09 12:40
Scientists have shed light on poorly understood brain mechanisms that suppress drug and alcohol cravings, uncovering new insights that may help in the development of better addiction medicines.
Categories: Drug Facts

Medical marijuana laws impact use among sexual minorities differently than heterosexuals

Drug Facts - Wed, 2019-09-04 09:32
Bisexual women had higher rates of past-year and daily marijuana use compared to heterosexual women, and gay/lesbian women were also more likely to report daily marijuana use and past year medical marijuana use than heterosexual women. While previous research has explored the association between state-level medical marijuana laws and marijuana use and MU disorder among the general US population, this is among the first to explore this relationship for lesbian, gay and bisexual individuals.
Categories: Drug Facts

Cannabis may hold promise to treat PTSD but evidence lags behind use

Drug Facts - Tue, 2019-09-03 17:42
As growing numbers of people are using cannabis to treat post-traumatic stress disorder (PTSD), a new study reports that prescriptions are not backed up by adequate evidence.
Categories: Drug Facts

Chronic cocaine use modifies gene expression

Drug Facts - Mon, 2019-09-02 11:53
Chronic cocaine use changes gene expression in the hippocampus, according to new research in mice.
Categories: Drug Facts

Drug use, excess alcohol and no helmet common among US injured eScooter users

Drug Facts - Thu, 2019-08-29 16:41
A significant proportion of eScooter injuries in the US seem to be occurring while 'drivers' are under the influence of drugs and/or alcohol and almost never wearing a helmet, suggests a new study.
Categories: Drug Facts

Gene linked to autism undergoes changes in men's sperm after pot use

Drug Facts - Tue, 2019-08-27 10:35
A specific gene associated with autism appears to undergo changes in the sperm of men who use marijuana, according to new research. The gene change occurs through a process called DNA methylation, and it could potentially be passed along to offspring.
Categories: Drug Facts

New breathalyzer can detect marijuana

Drug Facts - Tue, 2019-08-27 10:32
A team has developed a breathalyzer device that can measure the amount of tetrahydrocannabinol (THC), the psychoactive compound in marijuana, in the user's breath. The breathalyzer was developed using carbon nanotubes, tiny tubes of carbon 100,000 times smaller than a human hair. Nanotechnology sensors can detect THC at levels comparable to or better than mass spectrometry, which is considered the gold standard for THC detection.
Categories: Drug Facts

Teens are using a highly potent form of marijuana

Drug Facts - Mon, 2019-08-26 07:22
Nearly one in four Arizona teens have used a highly potent form of marijuana known as marijuana concentrate, according to a new study. Among nearly 50,000 eighth, 10th, and 12th graders from the 2018 Arizona Youth Survey, a biennial survey of Arizona secondary school students, one-third (33%) had tried some form of marijuana, and nearly a quarter (24%) had tried marijuana concentrate.
Categories: Drug Facts

Chocolate muddles cannabis potency testing

Drug Facts - Sun, 2019-08-25 05:59
Since the first states legalized recreational marijuana in 2012, several others have joined them, and cannabis-infused edibles, including gummy bears, cookies and chocolates, have flooded the market. But these sweet treats have created confusing results for scientists trying to analyze their potency and purity. Now researchers report that components in chocolate might be interfering with cannabis potency testing.
Categories: Drug Facts

Cannabis flower is an effective mid-level analgesic medication for pain

Drug Facts - Wed, 2019-08-21 10:55
Using the largest database of real-time recordings of the effects of common and commercially available cannabis products in the United States, researchers found strong evidence that cannabis can significantly alleviate pain, with the average user experiencing a three-point drop in pain suffering on a 0-10 point scale immediately following cannabis consumption.
Categories: Drug Facts

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